Chronic Fatigue Syndrome

Chronic Fatigue Syndrome (CFS) is a chronic disease and the individual shows extreme tiredness pain and sleep disorders that persist for a long time. CFS is also known as myalgic encephalomyelitis (ME) or systemic exertion intolerance disease. It is more common in women and might last for 6 months or more. The causes of CFS are unknown but some of the environmental or genetic factors might trigger the syndrome.

Symptoms: The symptoms vary in individuals.

• Ability to do normal or regular activities
• Difficulty in thinking
• Sleep disorders
• Severe headache
• Dizziness
• Joint pain
• Orthostatic intolerance, etc

Causes and Risk Factors:

Women are more likely to be diagnosed with CFS than men. This condition is rare in children. However, girls are more prone than boys. This condition is commonly seen in adults aged between 30-50 and in children aged between 13-15. CFS is genetic and is inherits the risk of it from one of its parents. Environmental factors of CFS may include - improper diet, stress, infectious organisms, etc. Other conditions that might be the underlying cause of CFS are - Fibromyalgia, Irritable bowel syndrome, Chronic pelvic pain, Chronic prostatitis, Temporomandibular disorders, Post-concussion syndrome, etc. Having any of these conditions could increase the risk of having CFS.

Treatment:

There is no cure for CFS. However, some medications can be prescribed to reduce and prevent the symptoms. Medications like muscle relaxants, Eszopiclone, Antidepressants, Benzodiazepines can be prescribed for sleep problems and pain relievers like aspirin, ibuprofen can be prescribed for joint pain. Alternative medications like acupuncture, nutritional supplements, relaxation therapy, yoga, etc can also help in providing relief.

Did you know?

Although the diagnosis of CFS is vague, scientists have now identified a blood test that might help in the diagnosis of CFS. The blood test shows changes in the electrical patterns of an individual's cells. When the cell is stressed, the difference in the electrical signal can be easily identified.

Another study showed that injecting lidocaine solution to the back muscles helped ease patients' fatigue. It was noted that, the muscles and other peripheral tissues for involved in chronic fatigue. Lidocaine thus helped in blocking the abnormal signaling of muscle metabolites.
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Announcement: 5th International Conference on Chronic Diseases

We are all set to introduce and welcome the participants from the global arena to the “5th International Conference on Chronic Diseases” on September 14-15, 2020 in Vienna, Austria. This year Chronic Disease 2020 is based on the theme ‘Exploring the Impact and Intervention”.

Chronic Disease 2020 extends an expert gathering, intended to connect, share and exchange ideas and views for promotion, prevention, treatment and care for chronic diseases. This chronic disease conference majorly focuses on the effective understanding of the disease origin, pathophysiology, risk factors and other clinical interpretations involved.

Experts from the academic and industrial community from all over the world will be joining us to share their most recent research works, patterns and findings. Chronic Disease 2020 will unite the worldwide pioneers in the field to display their investigations and studies along with other researchers. Young researchers can showcase their logical ideas and discoveries through oral sessions.

The 5th International Conference on Chronic Diseases is a two day event that will host about 40+ Scientific and technical sessions on leading and latest research trends related to the field.

Chronic Disease 2020 will provide the following to all the attendees.

• Creative lectures by speakers.

• Keynote forums by eminent Professors

• Poster presentations by Young Researchers

• Workshops and Symposiums

• Global Networking opportunities and Collaborations

• Meet with the editors, society and association members

Email: chronicdiseases@pulsusseries.com

Brain Protein Promotes the Maintenance of Chronic Pain

A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions.

The discovery may help doctors stop acute pain from progressing into chronic pain, a condition in which patients experience not just pain, but a number of debilitating symptoms ranging from sensory deficits to depression and loss of motivation. The transition from acute to chronic (pathological) pain is accompanied by numerous adaptations in immune, glial, and neuronal cells, many of which are still not well understood. As a result, currently available medications for neuropathic or chronic inflammatory pain show limited efficacy and major side effects. 

Commonly administered opioids provide a temporary alleviation of some pain symptoms but carry serious risks like addiction in the context of long-term treatment for chronic pain. Therefore, there is an imminent need for novel approaches towards the treatment of chronic pain and for the development of medications that disrupt pain states instead of simply alleviating symptoms.

RGS4 is a multifunctional protein widely expressed in brain circuits that process pathological pain, mood, and motivation. The genetic inactivation of RGS4 does not affect acute pain or the induction of chronic pain, it promotes recovery from sensory hypersensitivity symptoms in preclinical models of peripheral nerve injury, chemotherapy-induced neuropathy, and peripheral inflammation.

Credits: eurekalert.org

Bone Loss and Antiretroviral Therapy in HIV and HCV

Among the numerous comorbidities that affect people living with HIV (PLWH), an increased prevalence of osteopenia and osteoporosis has been observed across a range of studies. The etiology of reduced bone mineral density (BMD) in this population has been linked to various factors, including those associated with HIV infection and treatment, as well as unrelated factors.

As a result, PLWH has a greater prevalence of fractures compared with the general population, with one study showing rates of 2.87 vs 1.77 per 100 people per year, especially involving the spine, hip, and wrist.

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Chronic Diseases Prevention - A Glance

An Ounce of Prevention is Better than Pounds of Cure - Here are some of the important key facts to keep us away from the Chronic Diseases.

1. Physical Activity : Be active and keep going

2. Healthy Eating : Our health depends on what we are eating

3.Live Smoke Free

4.Limit your Alcohol Intake

5.Manage Your Stress : Relax

6.Get Screened for Cancer and Other Diseases

7.Get a Good Night Sleep

Being aware of the chronic diseases help us to be away from it.If you wish to join with us to share your knowledge on chronic diseases join with us in our annual meeting ( 4th International Conference on Chronic Diseases, Paris, France, February 17-18, 2020 ).

Combating Chronic Diseases: Technology and Innovation

According to recent statistics revealed by the Office for National Statistics (ONS) dementia including Alzheimer’s diseases is the leading cause of death in most of the countries.

What may be the cause for rising Chronic Conditions?

1.         Mass Urbanization
2.         Easily available convenient food
3.          Raise in sedentary work patterns

Digital Technologies and Chronic Diseases

Sooner in the upcoming days with the recent advancement in the fields of digital technologies, they will play an important role in preventing degenerative brain diseases such as dementia.

Tolerating the pain in chronic diseases is the most important fact when we deal with the area of chronic diseases management. In the next few years, the area of localized pain relief will be taken to the next level.

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Anemia and Chronic Diseases : The mystery Behind Chronic Diseases

Anemia of chronic diseases usually occurs as the part of chronic inflammatory disorder, most often chronic infection, autoimmune diseases, kidney diseases, or cancer.

Treatment to these types of anemia due to chronic conditions may include recombinant erythropoietin (EPO) and iron supplements.

These types of anemia are usually mild and in most of the cases transfusions are usually not required.

The list of chronic diseases that may cause anemia includes cancer, HIV/AIDS, Rhematoid arthritis, kidney diseases, crohn’s diseases, and other inflammatory disorders.

The important fact to be realized in this cases includes there is no specific treatment for this type of conditions doctors mainly focus on the treatment of underlying diseases.

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